Essential oil from fruit of Xylopia langsdorffiana: antitumour activity and toxicity
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چکیده
منابع مشابه
Antitumour properties of the leaf essential oil of Xylopia frutescens Aubl. (Annonaceae).
The aim of this study was to investigate the chemical composition and anticancer effect of the leaf essential oil of Xylopia frutescens in experimental models. The chemical composition of the essential oil was analysed by GC/FID and GC/MS. In vitro cytotoxic activity of the essential oil was determined on cultured tumour cells. In vivo antitumour activity was assessed in Sarcoma 180-bearing mic...
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Background and objectives: Ferula gummosa Boiss. (Umbelliferae) is a popular medicinal plant, which is known mostly for therapeutic uses of its oleo-gum-resin (Barijeh in Persian). In the present study, the essential oil of F. gummosa roots was investigated for its phytochemical constituents, antioxidant activity and toxicity potential. Method...
متن کاملIn vitro and in vivo antitumor effect of trachylobane-360, a diterpene from Xylopia langsdorffiana.
Trachylobane-360 (ent-7α-acetoxytrachyloban-18-oic acid) was isolated from Xylopia langsdorffiana. Studies have shown that it has weak cytotoxic activity against tumor and non-tumor cells. This study investigated the in vitro and in vivo antitumor effects of trachylobane-360, as well as its cytotoxicity in mouse erythrocytes. In order to evaluate the in vivo toxicological aspects related to tra...
متن کاملDiterpenes from Xylopia langsdorffiana inhibit cell growth and induce differentiation in human leukemia cells.
Two new diterpenes were isolated from stems and leaves of Xylopia langsdorffiana, ent-atisane-7alpha,16alpha-diol (xylodiol) and ent-7alpha-acetoxytrachyloban-18-oic acid (trachylobane), along with the known 8(17),12E,14-labdatrien-18-oic acid (labdane). We investigated their antitumour effects on HL60, U937 and K562 human leukemia cell lines. We found that xylodiol was the most potent diterpen...
متن کاملChemical constituents and anticancer effects of the essential oil from leaves of Xylopia laevigata.
Xylopia laevigata, popularly known as "meiú" and "pindaíba", is a medicinal plant used in the folk medicine of the Brazilian Northeast for several purposes. The chemical constituents of the essential oil from leaves of X. laevigata, collected from wild plants growing at three different sites of the remaining Atlantic forest in Sergipe State (Brazilian Northeast), were analyzed by GC/FID and GC/...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2016
ISSN: 1388-0209,1744-5116
DOI: 10.1080/13880209.2016.1211154